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Poster for Common Side Effects

TV series

Common Side Effects

2025 · TV-MA · 2 seasons · 11 episodes

Created by Joseph Bennett and Steve Hely

8.5

TMDB audience score
367 votes, out of 10

Trailer Where to watch

Synopsis

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

About 4h 13m to watch every episode. An estimate: 11 episodes at the typical episode runtime of 23 minutes.

TMDB lists the next episode for Jan 24, 2027.

Where to watch

Official options in the United States:

Subscription

  • HBO Max Amazon Channel
  • YouTube TV
  • Adult Swim
  • HBO Max

Free with ads

  • Adult Swim

Buy

  • Amazon Video
  • Apple TV Store
  • Google Play Movies
  • Fandango At Home

All options on TMDB

Where-to-watch data is provided by JustWatch through TMDB. It differs by country and changes over time, so confirm with the service before paying. PlotNest does not host or stream anything.

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Trailer

Play trailer: Official Trailer [Adult Swim Europe]

The preview image comes from YouTube. The player loads only after you press play.

Main cast

  • Dave King
    Marshall Cuso (voice)
    11 episodes

  • Emily Pendergast
    Frances Applewhite (voice)
    10 episodes

  • Mike Judge
    Rick Kruger (voice)
    10 episodes

  • Martha Kelly
    Agent Harrington (voice)
    10 episodes

  • Joseph Lee Anderson
    Agent Copano (voice)
    10 episodes

  • Sue Rose
    Hildy (voice)
    8 episodes

  • Shannon Woodward
    Amelia (voice)
    8 episodes

  • Ben Feldman
    Nick (voice)
    8 episodes

  • Sydney Tamiia Poitier
    Cecily (voice)
    7 episodes

  • Shalita Grant
    Female DEA Agent (voice)
    6 episodes

  • Danny Huston
    Jonas Backstein (voice)
    6 episodes

  • Steve Hely
    Rusty (voice)
    6 episodes

  • Christine Ko
    Kiki (voice)
    5 episodes

  • Alan Resnick
    Zane (voice)
    3 episodes

  • Lin Shaye
    Sonia (voice)
    3 episodes

  • Bob Stephenson
    Connor (voice)
    3 episodes

  • Timothy Simons
    DEA Dispatcher (voice)
    3 episodes

  • Jon Foor
    Hoang (voice)
    3 episodes

Seasons